Few experiments here and there:
Ok so bristol can take marker, lets try with the Canson comic paper and some digital flats.
its near decent but traditional shading with cool grays cant be edited, that kinda removes some options. Lets try some trad flats instead.
Ok getting better, ill have to buy an extra 90 color markers to do some real marker blending on these flats but its getting there, now lets try with a drawing that isnt as crappy.
Ok i think i got something, fast shadows on comp, fast flats on the go. Ill run a background test later today and start going overdrive with the next comic.